1,959 research outputs found

    The Chelsea Critical Care Physical Assessment Tool (CPAx): validation of an innovative new tool to measure physical morbidity in the general adult critical care population; an observational proof-of-concept pilot study.

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    Objective To develop a scoring system to measure physical morbidity in critical care – the Chelsea Critical Care Physical Assessment Tool (CPAx). Method The development process was iterative involving content validity indices (CVI), a focus group and an observational study of 33 patients to test construct validity against the Medical Research Council score for muscle strength, peak cough flow, Australian Therapy Outcome Measures score, Glasgow Coma Scale score, Bloomsbury sedation score, Sequential Organ Failure Assessment score, Short Form 36 (SF-36) score, days of mechanical ventilation and inter-rater reliability. Participants Trauma and general critical care patients from two London teaching hospitals. Results Users of the CPAx felt that it possessed content validity, giving a final CVI of 1.00 (P < 0.05). Construct validation data showed moderate to strong significant correlations between the CPAx score and all secondary measures, apart from the mental component of the SF-36 which demonstrated weak correlation with the CPAx score (r = 0.024, P = 0.720). Reliability testing showed internal consistency of α = 0.798 and inter-rater reliability of κ = 0.988 (95% confidence interval 0.791 to 1.000) between five raters. Conclusion This pilot work supports proof of concept of the CPAx as a measure of physical morbidity in the critical care population, and is a cogent argument for further investigation of the scoring system

    A New Genus of Cricetid Rodent from the Hemingfordian (Miocene) of Nebraska

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    5 p., 2 fig.http://paleo.ku.edu/contributions.htm

    Multi-Pulse Laser Wakefield Acceleration: A New Route to Efficient, High-Repetition-Rate Plasma Accelerators and High Flux Radiation Sources

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    Laser-driven plasma accelerators can generate accelerating gradients three orders of magnitude larger than radio-frequency accelerators and have achieved beam energies above 1 GeV in centimetre long stages. However, the pulse repetition rate and wall-plug efficiency of plasma accelerators is limited by the driving laser to less than approximately 1 Hz and 0.1% respectively. Here we investigate the prospects for exciting the plasma wave with trains of low-energy laser pulses rather than a single high-energy pulse. Resonantly exciting the wakefield in this way would enable the use of different technologies, such as fibre or thin-disc lasers, which are able to operate at multi-kilohertz pulse repetition rates and with wall-plug efficiencies two orders of magnitude higher than current laser systems. We outline the parameters of efficient, GeV-scale, 10-kHz plasma accelerators and show that they could drive compact X-ray sources with average photon fluxes comparable to those of third-generation light source but with significantly improved temporal resolution. Likewise FEL operation could be driven with comparable peak power but with significantly larger repetition rates than extant FELs

    Towards Load-Deformation Models for Screw-Fastened Cold-Formed Steel-to-Steel Shear Connections

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    This paper summarizes results from an experimental program considering single-fastened cold-formed steel-to-steel shear connections. Fastener motion (displacement and tilting angle) and bearing deformation occurring on the connecting members at the fastener location were captured using an automated, optical non-contact measurement procedure. The results are used to relate cold-formed steel-to-steel shear connection load-deformation response to tilting and bearing response. A general steel-to-steel single shear fastener load-deformation equation is also proposed and demonstrated

    Statistical analysis to develop a three-dimensional surface model of a midsize-male foot

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    A representative midsize-male foot was generated via a statistical analysis of foot scans from 107 men with widely varying body size. Seventy-two surface landmarks were manually extracted from the original scan data. A template fitting method was used to represent each scan with a homologous mesh. A principal component analysis and least-squares linear regression were used to generate a foot surface model with landmarks using a reference stature of 1755 mm and a body mass of 83.19 kg. The statistical model can be used to generate a wide range of male foot sizes and shapes.US Army Tank Automotive Research, Development, and Engineering Center (TARDEC)http://deepblue.lib.umich.edu/bitstream/2027.42/116596/1/103232.pdfDescription of 103232.pdf : Final repor

    Protecting File Systems with Transient Authentication

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    Laptops are vulnerable to theft, greatly increasing the likelihood of exposing sensitive files. Unfortunately, storing data in a cryptographic file system does not fully address this problem. Such systems ask the user to imbue them with long-term authority for decryption, but that authority can be used by anyone who physically possesses the machine. Forcing the user to frequently reestablish his identity is intrusive, encouraging him to disable encryption.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41362/1/11276_2004_Article_5384743.pd

    Laserwire at the Accelerator Test Facility 2 with Sub-Micrometre Resolution

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    A laserwire transverse electron beam size measurement system has been developed and operated at the Accelerator Test Facility 2 (ATF2) at KEK. Special electron beam optics were developed to create an approximately 1 x 100 {\mu}m (vertical x horizontal) electron beam at the laserwire location, which was profiled using a 150 mJ, 71 ps laser pulse with a wavelength of 532 nm. The precise characterisation of the laser propagation allows the non-Gaussian transverse profiles of the electron beam caused by the laser divergence to be deconvolved. A minimum vertical electron beam size of 1.07 ±{\pm} 0.06 (stat.) ±{\pm} 0.05 (sys.) {\mu}m was measured. A vertically focussing quadrupole just before the laserwire was varied whilst making laserwire measurements and the projected vertical emittance was measured to be 82.56 ±{\pm} 3.04 pm rad.Comment: 17 pages, 26 figures, submitted to Phys. Rev. ST Accel. Beam

    Evaluation of vegetation indices for rangeland biomass estimation in the Kimberley area of Western Australia

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    The objective of this paper is to test the relationships between Above Ground Biomass (AGB) and remotely sensed vegetation indices for AGB assessments in the Kimberley area in Western Australia. For 19 different sites, vegetation indices were derived from eight Landsat ETM+ scenes over a period of two years (2011–2013). The sites were divided into three groups (Open plains, Bunch grasses and Spinifex) based on similarities in dominant vegetation types. Dry and green biomass fractions were measured at these sites. Single and multiple regression relationships between vegetation indices and green and total AGB were calibrated and validated using a "leave site out" cross validation. Four tests were compared: (1) relationships between AGB and vegetation indices combining all sites; (2) separate relationships per site group; (3) multiple regressions including selected vegetation indices per site group; and (4) as in 3 but including rainfall and elevation data. Results indicate that relationships based on single vegetation indices are moderately accurate for green biomass in wide open plains covered with annual grasses. The cross-validation results for green AGB improved for a combination of indices for the Open plains and Bunch grasses sites, but not for Spinifex sites. When rainfall and elevation data are included, cross validation improved slightly with a Q2 of 0.49–0.72 for Open plains and Bunch grasses sites respectively. Cross validation results for total AGB were moderately accurate (Q2 of 0.41) for Open plains but weak or absent for other site groups despite good calibration results, indicating strong influence of site-specific factors

    Fault-controlled asymmetric landscapes and low-relief surfaces on Vestvågøya, Lofoten, North Norway: inherited Mesozoic rift-margin structures?

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    Source at https://dx.doi.org/10.17850/njg98-3-06The Lofoten Ridge is an integral basement horst of the hyperextended continental rift-margin off northern Norway. It is a key area for studying onshore–offshore rift-related faults, and for evaluating tectonic control on landscape development along the North Atlantic margin. This paper combines onshore geomorphological relief/aspect data and fault/fracture analysis with offshore bathymetric and seismic data, to demonstrate linkage of landscapes and Mesozoic rift-margin structures. At Leknes on Vestvågøya, an erosional remnant of a down-faulted Caledonian thrust nappe (Leknes Group) is preserved in a complex surface depression that extends across the entire Lofoten Ridge. This depression is bounded by opposing asymmetric mountains comprising fault-bounded steep scarps and gently dipping, partly incised lowrelief surfaces. Similar features and boundary faults of Palaeozoic–Mesozoic age are present on the offshore margin surrounding the Lofoten Ridge. The offshore margin is underlain by a crystalline, Permo–Triassic to Early Jurassic, peneplained basement surface that was successively truncated by normal faults, down-dropped and variably rotated into asymmetric fault blocks and basins in the Mesozoic, and the basins were subsequently filled by Late Jurassic to Early Cretaceous sedimentary strata. Comparison of the onshore asymmetric landscapes and offshore tectonic architecture supports the idea that disrupted low-relief surfaces, bounding steep scarps, ridges and depressions onshore the Lofoten Ridge, represent tectonic inheritance of a tilted basement-cover surface, rotated fault blocks and half-graben basins from Mesozoic rifting of the margin. In the Cenozoic, Mesozoic faults controlled the landscape by tilting and reactivated footwall uplift, followed by exhumation of the Mesozoic–Cenozoic cover sediments. Glacial erosion during the Pleistocene partly incised and modified these tectonic features, which nevertheless remain as distinct elements in the landscape
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